Voltaren Osteo Gel 12 Hourly has a higher concentration of inflammation-and-pain reducing active ingredient, NSAID diclofenac, than our Voltaren Emulgel. This means it provides up to 24 hour joint pain relief when you apply it once morning & evening; whilst still giving effective pain relief and reducing inflammation. Voltaren Osteo Gel 12 Hourly also contains a permeation enhancer for up to 3 times greater skin penetration. The active ingredient in Voltaren Osteo Gel 12 Hourly gets deep into the joint area to provide extended pain relief.